Anti-Estrogen Powder CAS 13647-35-3 Trilostane for Breast Cancer

Products DescriptionProduct nameTrilostaneCAS No.13647-35-3Molecular Formula C20H27NO3  Molecular weight  329.43  EINECS NO.  237-133-0  Grade Standard  Medicine Grade  COA  Avaliable Trilostane is an inhibitor of isoforms 3β-HSD

Featured Products

Products Description
Product nameTrilostane
CAS No.13647-35-3
Molecular Formula C20H27NO3 
 Molecular weight  329.43 
 EINECS NO.  237-133-0 
 Grade Standard  Medicine Grade 
 COA  Avaliable 

Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3∫-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of dihydrotestosterone in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.

Anti Estrogen Raw Powder CAS 13647-35-3 Trilostane for Breast Cancer
Anti Estrogen Raw Powder CAS 13647-35-3 Trilostane for Breast Cancer

Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.

For the treatment of post-menopausal women who have hormone-selective cancers that have spread beyond the breast, the medicine slows disease progression in two ways. Hormone-sensitive breast cancer, estrogen through the role of two kinds of receptors to promote cancer cell growth, estrogen receptor A like cancer accelerator, estrogen receptor beta is the brake. Modrenal enhances the estrogen receptor beta-estrogen adsorption, while reducing the role of the estrogen receptor a. At the same time it also acts on another site of cellular DNA AP1 to reduce cell proliferation.

Notes:Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.

  • Can help relieve excessive urination
  •  Encourages a healthy appetite
  •  Promotes balanced function of the adrenal and pituitary glands
  •  Promotes the healthy growth of skin and fur
  •  Supports the health of the endocrine system
  •  Works to enhances energy levels & stamina
  •  Works to reduce stress response in high strung or nervous pets


AppearanceWhite to tan powder.
Melting point264ºC
Boiling point467.02ºC(rough estimate)
Density1.1213 (rough estimate)
Specific rotation25 +137.4° (c = 1 in pyridine)
Refractive index1.5614 (estimate)
SolubilityDMSO: ≥17mg/mL
Storage condition-20ºC Freezer
Shelf life2 years

Package & Delivery

Anti Estrogen Raw Powder CAS 13647-35-3 Trilostane for Breast Cancer
By Express
By Air
By Sea
Suitable for under 50kg
Fast: 3-7 days
High cost
Door to door service,
easy to pick up the goods
Suitable for more than 50kg
Fast: 3-7 days
High cost
Port to port,
professional broker needed
Suitable for more than 500kg
Slow: 7-45 days
Low cost
Port to port,
professional broker needed

Anti Estrogen Raw Powder CAS 13647-35-3 Trilostane for Breast Cancer
Our services
1. All inquiries will be replied within 12 hours. 
2. Dedication to quality, supply & service. 
3. Strictly on selecting raw materials. 
3. OEM/ODM Available. 
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development. 
6. Faster delivery:Sample order in stock and 3-7 days for bulk production. 
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder. 
8. After-Sale Service: 
1) International Authorized Third-Party Test For The Products You Demand. 
2) 30 Days Warranty of quality of goods.

About us

Anti Estrogen Raw Powder CAS 13647-35-3 Trilostane for Breast Cancer

Q1.What's your MOQ? 
Our MOQ is 10pcs.

Q2: How to contact with us?
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.

Q3:Which kind of payment terms do you accept?
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.

Q4:Can you give me a discount price?
A: Sure,it depends on your quantity.

Q5:How can I get a sample?
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.

Q6: How to confirm the Product Quality before placing orders?
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.

Q7:How can I make payment safe?
A: The whole transaction is under Alibaba's (Third party) inspection.

Q8: Is it possible to custom the labels with our own design?
A: Yes, just send us your artworks, you will get what you want.
Q9.Can I get the sample?
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).

Q10.Can you accept customized?
Yes,we can according your require to do it.

Q11.How do I place the order?
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.

Contact us

Please feel free to give your inquiry in the form below We will reply you in 24 hours